Publication: Leukotriene and purinergic receptors are involved in the hyperpolarizing effect of glucagon in liver cells
Leukotriene and purinergic receptors are involved in the hyperpolarizing effect of glucagon in liver cells
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Fischer, L., Haag-Diergarten, S., Scharrer, E., & Lutz, T. A. (2005). Leukotriene and purinergic receptors are involved in the hyperpolarizing effect of glucagon in liver cells. Biochimica et Biophysica Acta, 1669(1), 26–33. https://doi.org/10.1016/j.bbamem.2005.01.010
Abstract
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The pancreatic hormone glucagon hyperpolarizes the liver cell membrane. In the present study, we investigated the cellular signalling pathway of glucagon-induced hyperpolarization of liver cells by using the conventional microelectrode method. The membrane potential was recorded in superficial liver cells of superfused mouse liver slices. In the presence of the K+ channel blockers tetraethylammonium (TEA, 1 mmol/l) and Ba2+ (BaCl2, 5 mmol/l) and the blocker of the Na+/K+ ATPase, ouabain (1 mmol/l), no glucagon-induced hyperpolarizatio
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- Fischer, Lisa
- Haag-Diergarten, Silke
- Scharrer, Erwin
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Fischer, L., Haag-Diergarten, S., Scharrer, E., & Lutz, T. A. (2005). Leukotriene and purinergic receptors are involved in the hyperpolarizing effect of glucagon in liver cells. Biochimica et Biophysica Acta, 1669(1), 26–33. https://doi.org/10.1016/j.bbamem.2005.01.010
