Publication: Roll, adhere, spread and contract: structural mechanics of platelet function
Roll, adhere, spread and contract: structural mechanics of platelet function
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Sorrentino, S., Studt, J.-D., Medalia, O., & Tanuj Sapra, K. (2015). Roll, adhere, spread and contract: structural mechanics of platelet function. European Journal of Cell Biology, 94, 129–138. https://doi.org/10.1016/j.ejcb.2015.01.001
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Platelets are involved in life-sustaining processes such as hemostasis, wound healing, atherothrombosis and angiogenesis. Mechanical trauma to blood vessels causes platelet activation resulting in their adherence and clot formation at the damaged site, culminating in clot retraction and tissue repair. Two of the major players underlying this process are the cytoskeleton, i.e., actin and microtubules, and the membrane integrin receptors. Rare congenital bleeding disorders such as Glanzmann thrombasthenia and Bernard-Soulier syndrome ar
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- Sorrentino, Simona
- Studt, Jan-Dirk
- Medalia, Ohad
- Tanuj Sapra, K
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Sorrentino, S., Studt, J.-D., Medalia, O., & Tanuj Sapra, K. (2015). Roll, adhere, spread and contract: structural mechanics of platelet function. European Journal of Cell Biology, 94, 129–138. https://doi.org/10.1016/j.ejcb.2015.01.001
