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Toward a Smartphone-Based and Conversational Agent–Delivered Just-in-Time Adaptive Holistic Lifestyle Intervention for Older Adults Affected by Cognitive Decline: Two-Week Proof-of-Concept Study

Date

Date

Date
2025
Journal Article
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Brill, E., Vinay, R., Nißen, M., Joshi, P., Klöppel, S., & Kowatsch, T. (2025). Toward a Smartphone-Based and Conversational Agent–Delivered Just-in-Time Adaptive Holistic Lifestyle Intervention for Older Adults Affected by Cognitive Decline: Two-Week Proof-of-Concept Study. JMIR Formative Research, 9, e66885. https://doi.org/10.2196/66885

Abstract

Abstract

Abstract

Background Dementia is projected to impact 152 million people by 2050, making it one of the most pressing global health challenges. The neurodegenerative process initiates well before clinical symptoms manifest, advancing from subjective cognitive decline (SCD) to mild cognitive impairment (MCI) and ultimately to dementia. Despite the growing prevalence, awareness of dementia prevention is limited, and many individuals express a desire to cease living upon diagnosis. Lifestyle interventions can mitigate cognitive decline, but there i

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2 since deposited on 2025-11-12
Acq. date: 2025-11-14

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2 since deposited on 2025-11-12
Acq. date: 2025-11-14

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Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
9

Page range/Item number

Page range/Item number

Page range/Item number
e66885

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

smartphone-based, aging, awareness, cognitive impairment, conversational agents, dementia, dementia prevention, digital, digital health, digital health interventions, feasibility, global health, health intervention, just-in-time adaptive intervention, mHealth, mobile health, mobile phone, older adults, older person, single-arm feasibility study, smartphone, technology

Language

Language

Language
English

Publication date

Publication date

Publication date
2025-07-28

Date available

Date available

Date available
2025-11-12

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2561-326X

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
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PubMed ID

PubMed ID

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Downloads

2 since deposited on 2025-11-12
Acq. date: 2025-11-14

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2 since deposited on 2025-11-12
Acq. date: 2025-11-14

Citations

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Citation copied

Brill, E., Vinay, R., Nißen, M., Joshi, P., Klöppel, S., & Kowatsch, T. (2025). Toward a Smartphone-Based and Conversational Agent–Delivered Just-in-Time Adaptive Holistic Lifestyle Intervention for Older Adults Affected by Cognitive Decline: Two-Week Proof-of-Concept Study. JMIR Formative Research, 9, e66885. https://doi.org/10.2196/66885

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