Long-Term Hypothermia in Patients with Severe Brain Edema After Poor-Grade Subarachnoid Hemorrhage Feasibility and Intensive Care Complications

Gasser, Stefan; Khan, Nadia; Yonekawa, Yasuhiro; Imhof, Hans-Georg; Keller, Emanuela

doi:10.5167/uzh-192123

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Gasser, S., Khan, N., Yonekawa, Y., Imhof, H.-G., & Keller, E. (2003). Long-Term Hypothermia in Patients with Severe Brain Edema After Poor-Grade Subarachnoid Hemorrhage Feasibility and Intensive Care Complications. Journal of Neurosurgical Anesthesiology, 15, 240–248. https://doi.org/10.1097/00008506-200307000-00012

Abstract

The purpose was to evaluate the feasibility and intensive care complications of long-term hypothermia (>72 hours) in the treatment of severe brain edema after poor-grade subarachnoid hemorrhage (SAH) Hunt and Hess grade 4 to 5. Among 156 patients with SAH, 21 patients were treated with mild hypothermia (33.0 to 34.0 degrees C) combined with barbiturate coma because of severe brain edema and elevated intracranial pressure (>15 mm Hg) after early aneurysm clipping. Hypothermia was sustained for at least 24 hours after maintaining an int