Publication:

Genome-wide profiling to analyze the effects of high fat diet induced obesity on renal gene expression in mouse with reduced renal mass

Date

Date

Date
2014
Journal Article
Published version

Citations

Citation copied

Gai, Z. (2014). Genome-wide profiling to analyze the effects of high fat diet induced obesity on renal gene expression in mouse with reduced renal mass. Genomics Data, 2, 42–43. https://doi.org/10.1016/j.gdata.2014.02.002

Abstract

Abstract

Abstract

To assess the relationship between a reduced nephron number and a particular susceptibility to obesity-induced renal damage, mice underwent uninephrectomy (UNX) followed by either normal chow or high-fat diet (HFD) and were compared with sham-operated control mice. Analysis of gene expression in the mouse kidney by whole genome microarrays indicated that high fat diet led to more changes in gene expression than uninephrectomy. However, the combination of UNX and HFD additionally altered the effects of obesity on gene expression patter

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44 since deposited on 2015-02-05
Acq. date: 2025-11-08

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101 since deposited on 2015-02-05
Acq. date: 2025-11-08

Additional indexing

Creators (Authors)

  • Gai, Zhibo
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
2

Page Range

Page Range

Page Range
42

Page end

Page end

Page end
43

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Chronic kidney failure, Gene regulation, High fat diet, Microarray

Language

Language

Language
English

Publication date

Publication date

Publication date
2014

Date available

Date available

Date available
2015-02-05

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2213-5960

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

44 since deposited on 2015-02-05
Acq. date: 2025-11-08

Views

101 since deposited on 2015-02-05
Acq. date: 2025-11-08

Citations

Citation copied

Gai, Z. (2014). Genome-wide profiling to analyze the effects of high fat diet induced obesity on renal gene expression in mouse with reduced renal mass. Genomics Data, 2, 42–43. https://doi.org/10.1016/j.gdata.2014.02.002

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Files
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Files

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