Publication: Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude
Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude
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Siebenmann, C., Rasmussen, P., Hug, M., Keiser, S., Flück, D., Fisher, J. P., Hilty, M. P., Maggiorini, M., & Lundby, C. (2017). Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude. Journal of Physiology, 595(5), 1619–1626. https://doi.org/10.1113/JP273726
Abstract
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Abstract
KEY POINTS Heart rate is increased in chronic hypoxia and we tested whether this is the result of increased sympathetic nervous activity, reduced parasympathetic nervous activity, or a non-autonomic mechanism. In seven lowlanders, heart rate was measured at sea level and after 2 weeks at high altitude after individual and combined pharmacological inhibition of sympathetic and/or parasympathetic control of the heart. Inhibition of parasympathetic control of the heart alone or in combination with inhibition of sympathetic control abolis
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Creators (Authors)
- Siebenmann, Christoph
- Rasmussen, Peter
- Hug, Mike
- Keiser, Stefanie
- Flück, Daniela
- Fisher, James P
- Hilty, Matthias P
- Maggiorini, Marco
- Lundby, Carsten
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Siebenmann, C., Rasmussen, P., Hug, M., Keiser, S., Flück, D., Fisher, J. P., Hilty, M. P., Maggiorini, M., & Lundby, C. (2017). Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude. Journal of Physiology, 595(5), 1619–1626. https://doi.org/10.1113/JP273726
