Publication: Synthesis of tripeptide derivatized cyclopentadienyl complexes of Technetium and Rhenium as radiopharmaceutical probes
Synthesis of tripeptide derivatized cyclopentadienyl complexes of Technetium and Rhenium as radiopharmaceutical probes
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Nadeem, Q., Can, D., Shen, Y., Felber, M., Mahmood, Z., & Alberto, R. (2014). Synthesis of tripeptide derivatized cyclopentadienyl complexes of Technetium and Rhenium as radiopharmaceutical probes. Organic & Biomolecular Chemistry, 12(12), 1966–1974. https://doi.org/10.1039/c3ob41866a
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We describe the syntheses of half-sandwich complexes of the type [(η$^5$-Cp(CONH-R))M(CO)$_3$] with M = Re or $^{99m}$Tc. The R group represents different tri-peptides (tpe) which display high binding affinities for oligopeptide transporters PEPT2. The $^{99m}$Tc complexes were prepared directly from [$^{99m}$Tc(OH$_2$)$_3$(CO)$_3$
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- Nadeem, Qaisar
- Can, Daniel
- Shen, Yunjun
- Felber, Michael
- Mahmood, Zaid
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Nadeem, Q., Can, D., Shen, Y., Felber, M., Mahmood, Z., & Alberto, R. (2014). Synthesis of tripeptide derivatized cyclopentadienyl complexes of Technetium and Rhenium as radiopharmaceutical probes. Organic & Biomolecular Chemistry, 12(12), 1966–1974. https://doi.org/10.1039/c3ob41866a