Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation

Mayinger, Michael; Boda-Heggemann, Judit; Mehrhof, Felix; Krug, David; Hohmann, Stephan; Xie, Jingyang; Ehrbar, Stefanie; Kovacs, Boldizsar; Merten, Roland; Grehn, Melanie; Zaman, Adrian; Fleckenstein, Jens; Kaestner, Lena; Buergy, Daniel; Rudic, Boris; Kluge, Anne; Boldt, Leif-Hendrik; Dunst, Jürgen; Bonnemeier, Hendrik; Saguner, Ardan M

doi:10.1016/j.phro.2022.12.003

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Mayinger, M., Boda-Heggemann, J., Mehrhof, F., Krug, D., Hohmann, S., Xie, J., Ehrbar, S., Kovacs, B., Merten, R., Grehn, M., Zaman, A., Fleckenstein, J., Kaestner, L., Buergy, D., Rudic, B., Kluge, A., Boldt, L.-H., Dunst, J., Bonnemeier, H., … Schweikard, A. (2023). Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation. Physics and Imaging in Radiation Oncology, 25, 100406. https://doi.org/10.1016/j.phro.2022.12.003

Abstract

A novel quality assurance process for electroanatomical mapping (EAM)-to-radiotherapy planning imaging (RTPI) target transport was assessed within the multi-center multi-platform framework of the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial. A stand-alone software (CARDIO-RT) was developed to enable platform independent registration of EAM and RTPI of the left ventricle (LV), based on pre-generated radiotherapy contours (RTC). LV-RTC were automatically segmented into the American-Heart-Association 17-segment-model and a ma