Publication: Animal models for studying microglia: The first, the popular, and the new
Animal models for studying microglia: The first, the popular, and the new
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Sieger, D., & Peri, F. (2013). Animal models for studying microglia: The first, the popular, and the new. Glia, 61(1), 3–9. https://doi.org/10.1002/glia.22385
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Microglia, the resident phagocytes of brain, have been intensively studied since their discovery in the 1920s. There is no doubt that the possibility of culturing microglia in vitro has advanced enormously our understanding of these cells. However, as we know today, that microglia react to even small changes in the brain, it is crucial to also study these cells by preserving as much as possible their natural environment. Nowadays, advances in imaging technologies and transgenic cell labeling methods allow the direct observation of cel
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Sieger, D., & Peri, F. (2013). Animal models for studying microglia: The first, the popular, and the new. Glia, 61(1), 3–9. https://doi.org/10.1002/glia.22385