Publication: Effects of dexamethasone-21-isonicotinate on peripheral insulin action in dairy cows 5 days after surgical correction of abomasal displacement
Effects of dexamethasone-21-isonicotinate on peripheral insulin action in dairy cows 5 days after surgical correction of abomasal displacement
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Kusenda, M., Kaske, M., Piechotta, M., Locher, L., Starke, A., Huber, K., & Rehage, J. (2013). Effects of dexamethasone-21-isonicotinate on peripheral insulin action in dairy cows 5 days after surgical correction of abomasal displacement. Journal of Veterinary Internal Medicine, 27(1), 200–206. https://doi.org/10.1111/jvim.12010
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BACKGROUND: Dexamethasone frequently is used for treatment of ketosis in dairy cows, but its effects are not fully understood. HYPOTHESIS: Dexamethasone treatment affects whole body insulin sensitivity. ANIMALS: Twelve German Holstein cows, 2-4 weeks postpartum, 5 days after omentopexy to correct left abomasal displacement. METHODS: Randomized, blinded, case-control study. Treatment with dexamethasone-21-isonicotinate (DG; 40 μg/kg IM; n = 6) or saline (control group [CG], 15 mL IM, n = 6) on day 0 (d0). Blood samples were obtained be
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- Kusenda, M
- Kaske, M
- Piechotta, M
- Locher, L
- Starke, A
- Huber, K
- Rehage, J
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Kusenda, M., Kaske, M., Piechotta, M., Locher, L., Starke, A., Huber, K., & Rehage, J. (2013). Effects of dexamethasone-21-isonicotinate on peripheral insulin action in dairy cows 5 days after surgical correction of abomasal displacement. Journal of Veterinary Internal Medicine, 27(1), 200–206. https://doi.org/10.1111/jvim.12010