Publication: Relevance of periostin splice variants in renal cell carcinoma
Relevance of periostin splice variants in renal cell carcinoma
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Morra, L., Rechsteiner, M., Casagrande, S., Duc Luu, V., Santimaria, R., Diener, P. A., Sulser, T., Kristiansen, G., Schraml, P., Moch, H., & Soltermann, A. (2011). Relevance of periostin splice variants in renal cell carcinoma. American Journal of Pathology, 179(3), 1513–1521. https://doi.org/10.1016/j.ajpath.2011.05.035
Abstract
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Abstract
The extracellular matrix N-glycoprotein periostin is thought to enhance tumor invasion. In this study, the expression patterns of periostin and its splice isoforms were investigated in renal cell carcinoma (RCC). Periostin mRNA expression patterns were characterized in 30 fresh-frozen RCCs in normal fetal and adult renal tissues by both isoform-specific and nonspecific RT-PCR and by gene expression array analysis. Its protein expression was analyzed by immunohistochemistry, using tissue microarrays with tissue from 1007 RCC patients.
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Morra, L., Rechsteiner, M., Casagrande, S., Duc Luu, V., Santimaria, R., Diener, P. A., Sulser, T., Kristiansen, G., Schraml, P., Moch, H., & Soltermann, A. (2011). Relevance of periostin splice variants in renal cell carcinoma. American Journal of Pathology, 179(3), 1513–1521. https://doi.org/10.1016/j.ajpath.2011.05.035