Publication:

Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity

Date

Date

Date
2023
Journal Article
Published version

Citations

Citation copied

Thomson, B. R., Richter, H., Akeret, K., Buzzi, R. M., Anagnostakou, V., van Niftrik, C. H. B., Schwendinger, N., Kulcsar, Z., Kronen, P. W., Regli, L., Fierstra, J., Schaer, D. J., & Hugelshofer, M. (2023). Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity. Journal of Stroke and Cerebrovascular Diseases, 32, 106985. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.106985

Abstract

Abstract

Abstract

Objectives: Cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). Haptoglobin scavenging of CSF-Hb has been shown to mitigate cerebrovascular disruption. Using digital subtraction angiography (DSA) and blood oxygenation-level dependent cerebrovascular reactivity imaging (BOLD-CVR) the aim was to assess the acute toxic effect of CSF-Hb on cerebral blood flow and autoregulation, as well as to test the protective effects of haptog

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4 since deposited on 2023-04-18
Acq. date: 2025-11-13

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1 since deposited on 2023-04-18
Acq. date: 2025-11-13

Additional indexing

Creators (Authors)

  • Thomson, Bart R
    affiliation.icon.alt
  • Richter, Henning
    affiliation.icon.alt
  • Akeret, Kevin
    affiliation.icon.alt
  • Anagnostakou, Vania
    affiliation.icon.alt
  • van Niftrik, Christiaan H B
    affiliation.icon.alt
  • Schwendinger, Nina
    affiliation.icon.alt
  • Kulcsar, Zsolt
    affiliation.icon.alt
  • Kronen, Peter W
    affiliation.icon.alt
  • Regli, Luca
    affiliation.icon.alt
  • Fierstra, Jorn
    affiliation.icon.alt
  • Schaer, Dominik J
    affiliation.icon.alt
  • Hugelshofer, Michael
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
32

Number

Number

Number
3

Page range/Item number

Page range/Item number

Page range/Item number
106985

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Cardiology and Cardiovascular Medicine, Neurology (clinical), Rehabilitation, Surgery

Language

Language

Language
English

Publication date

Publication date

Publication date
2023-03-01

Date available

Date available

Date available
2023-04-18

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1052-3057

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

4 since deposited on 2023-04-18
Acq. date: 2025-11-13

Views

1 since deposited on 2023-04-18
Acq. date: 2025-11-13

Citations

Citation copied

Thomson, B. R., Richter, H., Akeret, K., Buzzi, R. M., Anagnostakou, V., van Niftrik, C. H. B., Schwendinger, N., Kulcsar, Z., Kronen, P. W., Regli, L., Fierstra, J., Schaer, D. J., & Hugelshofer, M. (2023). Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity. Journal of Stroke and Cerebrovascular Diseases, 32, 106985. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.106985

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