Publication: A short bout of HFD promotes long-lasting hepatic lipid accumulation
A short bout of HFD promotes long-lasting hepatic lipid accumulation
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Chiazza, F., Challa, T. D., Lucchini, F. C., Konrad, D., & Wueest, S. (2016). A short bout of HFD promotes long-lasting hepatic lipid accumulation. Adipocyte, 5(1), 88–92. https://doi.org/10.1080/21623945.2015.1071454
Abstract
Abstract
Abstract
A short bout of high fat diet (HFD) impairs glucose tolerance and induces hepatic steatosis in mice. Here, we aimed to elaborate on long-lasting effects of short-term high fat feeding. As expected, one week of HFD significantly impaired glucose tolerance. Intriguingly, recovery feeding with a standard rodent diet for 8 weeks did not fully normalize glucose tolerance. In addition, mice exposed to a short bout of HFD revealed significantly increased liver fat accumulation paralleled by elevated portal free fatty acid levels after 8 week
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- Chiazza, Fausto
- Challa, Tenagne D
- Lucchini, Fabrizio C
- Wueest, Stephan
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Chiazza, F., Challa, T. D., Lucchini, F. C., Konrad, D., & Wueest, S. (2016). A short bout of HFD promotes long-lasting hepatic lipid accumulation. Adipocyte, 5(1), 88–92. https://doi.org/10.1080/21623945.2015.1071454
