Publication: Executive functions in healthy older adults are differentially related to macro- and microstructural white matter characteristics of the cerebral lobes
Executive functions in healthy older adults are differentially related to macro- and microstructural white matter characteristics of the cerebral lobes
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Hirsiger, S., Koppelmans, V., Mérillat, S., Erdin, C., Narkhede, A., Brickman, A. M., & Jäncke, L. (2017). Executive functions in healthy older adults are differentially related to macro- and microstructural white matter characteristics of the cerebral lobes. Frontiers in Aging Neuroscience, 9, 373. https://doi.org/10.3389/fnagi.2017.00373
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Aging is associated with microstructural white matter (WM) changes. WM microstructural characteristics, measured with diffusion tensor imaging (DTI), are different in normal appearing white matter (NAWM) and WM hyperintensities (WMH). It is largely unknown how the microstructural properties of WMH are associated with cognition and if there are regional effects for specific cognitive domains. We therefore examined within 200 healthy older participants (a) differences in microstructural characteristics of NAWM and WMH per cerebral lobe;
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Hirsiger, S., Koppelmans, V., Mérillat, S., Erdin, C., Narkhede, A., Brickman, A. M., & Jäncke, L. (2017). Executive functions in healthy older adults are differentially related to macro- and microstructural white matter characteristics of the cerebral lobes. Frontiers in Aging Neuroscience, 9, 373. https://doi.org/10.3389/fnagi.2017.00373