Publication: Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?
Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?
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Slankamenac, K., Breitenstein, S., Beck-Schimmer, B., Graf, R., Puhan, M. A., & Clavien, P.-A. (2012). Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery? HPB, 14, 854–862. https://doi.org/10.1111/j.1477-2574.2012.00570.x
Abstract
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BACKGROUND: A recently published randomized control trial (RCT) showed a protection of the remnant liver from ischemia-reperfusion (I/R) injury by pharmacological pre-conditioning with a volatile anaesthetic in patients undergoing hepatic resection. Whether the continuous application of volatile anaesthetics (pharmacological conditioning) also protects against I/R injury is unknown. METHODS: Consecutive patients undergoing liver resection with inflow occlusion from 2005-2007 were included in the trial. Two groups of anaesthesia regime
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- Slankamenac, Ksenija
- Breitenstein, Stefan
- Beck-Schimmer, Beatrice
- Graf, Rolf
- Puhan, Milo A
- Clavien, Pierre-Alain
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Slankamenac, K., Breitenstein, S., Beck-Schimmer, B., Graf, R., Puhan, M. A., & Clavien, P.-A. (2012). Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery? HPB, 14, 854–862. https://doi.org/10.1111/j.1477-2574.2012.00570.x
