True survival benefit of lung transplantation for cystic fibrosis patients: the Zurich experience

Hofer, M; Benden, C; Inci, I; Schmid, C; Irani, S; Speich, R; Weder, W; Boehler, A

doi:10.5167/uzh-19724

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Hofer, M., Benden, C., Inci, I., Schmid, C., Irani, S., Speich, R., Weder, W., & Boehler, A. (2009). True survival benefit of lung transplantation for cystic fibrosis patients: the Zurich experience. Journal of Heart and Lung Transplantation, 28(4), 334–339. https://doi.org/10.1016/j.healun.2008.12.025

Abstract

BACKGROUND: Lung transplantation is the ultimate therapy for end-stage cystic fibrosis (CF) lung disease; however, the debate continues as to whether lung transplantation improves survival. We report post-transplant outcome in CF at our institution by comparing 5-year post-transplant survival with a calculated 5-year survival without lung transplantation, using a predictive 5-year survivorship model, and describe pre-transplant parameters influencing transplant outcome. METHODS: CF patients undergoing lung transplantation at our cente