Publication: Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster
Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster
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Trost, M., Blattner, A. C., & Lehner, C. F. (2016). Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster. Fly, 10(1), 35–46. https://doi.org/10.1080/19336934.2016.1168552
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The analysis of consequences resulting after experimental elimination of gene function has been and will continue to be an extremely successful strategy in biological research. Mutational elimination of gene function has been widely used in the fly Drosophila melanogaster. RNA interference is used extensively as well. In the fly, exceptionally precise temporal and spatial control over elimination of gene function can be achieved in combination with sophisticated transgenic approaches and clonal analyses. However, the methods that act
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Trost, M., Blattner, A. C., & Lehner, C. F. (2016). Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster. Fly, 10(1), 35–46. https://doi.org/10.1080/19336934.2016.1168552