Publication: Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease
Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease
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Müller, T., Riederer, P., & Grünblatt, E. (2017). Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson’s disease. Journal of Neural Transmission, 124(6), 745–748. https://doi.org/10.1007/s00702-017-1705-z
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We determined monoamine oxidase-A (plasma) and -B (platelets) enzyme activity in chronic levodopa treated patients with Parkinson's disease after first time intake of an irreversible monoamine oxidase-B inhibitor. One patient received 10 mg selegiline and eleven patients took 1 mg rasagiline. A significant decrease of monoamine oxidase-B activity appeared 2 and 4 h following monoamine oxidase-B inhibitor intake in comparison to baseline. We confirm with this design, that rasagiline and selegiline inhibit monoamine oxidase-B but not mo
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- Müller, Thomas
- Riederer, Peter
- Grünblatt, Edna
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Müller, T., Riederer, P., & Grünblatt, E. (2017). Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson’s disease. Journal of Neural Transmission, 124(6), 745–748. https://doi.org/10.1007/s00702-017-1705-z
