Publication: Lung Based Engineered Micro-Pancreas Sustains Human Beta Cell Survival and Functionality
Lung Based Engineered Micro-Pancreas Sustains Human Beta Cell Survival and Functionality
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Goldman, O., Puchinsky, D., Durlacher, K., Sancho, R., Ludwig, B., Kugelmeier, P., Heller, C., Kunicher, N., Bornstein, S. R., & Treves, A. J. (2019). Lung Based Engineered Micro-Pancreas Sustains Human Beta Cell Survival and Functionality. Hormone and Metabolic Research, 51(12), 805–811. https://doi.org/10.1055/a-1041-3305
Abstract
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The whole world has been affected by a dramatically increasing prevalence of diabetes. Today, the etiology of both type 1 and type 2 diabetes is thought to revolve around the dysfunction of β-cells, the insulin producing cells of the body. Within the pharmaceutical industry, the evaluation of new drugs for diabetes treatment is mostly done using cell lines or rodent islets and depends solely on the assessment of static insulin secretion. However, the use of cell lines or rodent islets is limiting lack of similarity of the human islet
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- Goldman, Orit
- Puchinsky, Dmitry
- Durlacher, Karina
- Sancho, Rocio
- Ludwig, Barbara
- Kugelmeier, Patrick
- Heller, Carolin
- Kunicher, Nikolai
- Bornstein, Stefan R
- Treves, Avraham J
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Goldman, O., Puchinsky, D., Durlacher, K., Sancho, R., Ludwig, B., Kugelmeier, P., Heller, C., Kunicher, N., Bornstein, S. R., & Treves, A. J. (2019). Lung Based Engineered Micro-Pancreas Sustains Human Beta Cell Survival and Functionality. Hormone and Metabolic Research, 51(12), 805–811. https://doi.org/10.1055/a-1041-3305
