Publication: Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice
Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice
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Tarasco, E., Boyle, C. N., Pellegrini, G., Arnold, M., Steiner, R., Hornemann, T., Nasias, D., Kardassis, D., Whiting, L., & Lutz, T. A. (2019). Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice. International Journal of Obesity, 43(12), 2394–2406. https://doi.org/10.1038/s41366-019-0408-y
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BACKGROUND/OBJECTIVES: The incidence of obesity and metabolic syndrome (MetS) has rapidly increased worldwide. Roux-en-Y gastric bypass (RYGB) achieves long-term weight loss and improves MetS-associated comorbidities. Using a mouse model with a humanized lipoprotein metabolism, we elucidated whether improvements in lipid and glucose metabolism after RYGB surgery are body weight loss-dependent or not. SUBJECTS/METHODS: Male ApoE*3Leiden.CETP (ApoE3L.CETP) mice fed Western type diet for 6 weeks underwent RYGB or Sham surgery. Sham group
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- Tarasco, Erika
- Boyle, Christina N
- Pellegrini, Giovanni
- Arnold, Myrtha
- Steiner, Regula
- Nasias, Dimitris
- Kardassis, Dimitris
- Whiting, Lynda
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Tarasco, E., Boyle, C. N., Pellegrini, G., Arnold, M., Steiner, R., Hornemann, T., Nasias, D., Kardassis, D., Whiting, L., & Lutz, T. A. (2019). Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice. International Journal of Obesity, 43(12), 2394–2406. https://doi.org/10.1038/s41366-019-0408-y
