Publication: Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection
Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection
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Abela, I. A., Schwarzmüller, M., Ulyte, A., Radtke, T., Haile, S. R., Ammann, P., Raineri, A., Rueegg, S., Epp, S., Berger, C., Böni, J., Manrique, A., Audigé, A., Huber, M., Schreiber, P. W., Scheier, T., Fehr, J., Weber, J., Rusert, P., … Pasin, C. (2024). Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection. MBio, 15, e0272223. https://doi.org/10.1128/mbio.02722-23
Abstract
Abstract
Abstract
Knowledge of the interplay between human coronavirus (HCoV) immunity and severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection is critical to understanding the coexistence of current endemic coronaviruses and to building knowledge potential future zoonotic coronavirus transmissions. This study, which retrospectively analyzed a large cohort of individuals first exposed to SARS-CoV-2 in Switzerland in 2020–2021, revealed several key findings. Pre-existing HCoV immunity, particularly mucosal antibody responses, play
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Creators (Authors)
- Abela, Irene A
- Schwarzmüller, Magdalena
- Ulyte, Agne
- Radtke, Thomas
- Ammann, Priska
- Raineri, Alessia
- Rueegg, Sonja
- Epp, Selina
- Böni, Jürg
- Audigé, Annette
- Schreiber, Peter W
- Scheier, Thomas
- Fehr, Jan
- Weber, Jacqueline
- Rusert, Peter
- Günthard, Huldrych F
- Kouyos, Roger D
- Puhan, Milo A
- Kriemler, Susi
- Pasin, Chloé
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Abela, I. A., Schwarzmüller, M., Ulyte, A., Radtke, T., Haile, S. R., Ammann, P., Raineri, A., Rueegg, S., Epp, S., Berger, C., Böni, J., Manrique, A., Audigé, A., Huber, M., Schreiber, P. W., Scheier, T., Fehr, J., Weber, J., Rusert, P., … Pasin, C. (2024). Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection. MBio, 15, e0272223. https://doi.org/10.1128/mbio.02722-23
