Publication: Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading scheme
Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading scheme
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Ohashi, R., Martignoni, G., et al, Schraml, P., Rupp, N. J., & Moch, H. (2020). Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading scheme. Virchows Archiv, 476(3), 409–418. https://doi.org/10.1007/s00428-019-02710-w
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A histological grading system of chromophobe renal cell carcinoma (chRCC) is highly desirable to identify approximately 5-10% of tumors at risk for progression. Validation studies failed to demonstrate a correlation between the four-tiered WHO/ISUP grade and outcome. Previous proposals with three-tiered chromophobe grading systems could not be validated. In this study, the presence of sarcomatoid differentiation, necrosis, and mitosis was analyzed in a Swiss cohort (n = 42), an Italian cohort (n = 103), a German cohort (n = 54), a Jap
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- Ohashi, Riuko
- Martignoni, Guido
- Schraml, Peter
- Rupp, N J
- Moch, Holger
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Ohashi, R., Martignoni, G., et al, Schraml, P., Rupp, N. J., & Moch, H. (2020). Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading scheme. Virchows Archiv, 476(3), 409–418. https://doi.org/10.1007/s00428-019-02710-w
