Publication: Using enzymatic amplification by aldolase for the optical detection of DNA by an artificial signal cascade
Using enzymatic amplification by aldolase for the optical detection of DNA by an artificial signal cascade
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Graf, N., Kassube, S. A., & Krämer, R. (2008). Using enzymatic amplification by aldolase for the optical detection of DNA by an artificial signal cascade. Bioorganic & Medicinal Chemistry Letters, 18(17), 4786–4788. https://doi.org/10.1016/j.bmcl.2008.07.102
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A two-step reaction cascade is applied to the sequence-specific detection of single-stranded DNA, including analyte-triggered re-activation of apo-aldolase by its cofactor Zn(2+) and catalytic conversion of a chromophore.
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- Graf, Nora
- Krämer, Roland
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Graf, N., Kassube, S. A., & Krämer, R. (2008). Using enzymatic amplification by aldolase for the optical detection of DNA by an artificial signal cascade. Bioorganic & Medicinal Chemistry Letters, 18(17), 4786–4788. https://doi.org/10.1016/j.bmcl.2008.07.102