Publication: Microbial life cycles link global modularity in regulation to mosaic evolution
Microbial life cycles link global modularity in regulation to mosaic evolution
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van Gestel, J., Ackermann, M., & Wagner, A. (2019). Microbial life cycles link global modularity in regulation to mosaic evolution. Nature Ecology and Evolution, 3(8), 1184–1196. https://doi.org/10.1038/s41559-019-0939-6
Abstract
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Microbes are exposed to changing environments, to which they can respond by adopting various lifestyles such as swimming, colony formation or dormancy. These lifestyles are often studied in isolation, thereby giving a fragmented view of the life cycle as a whole. Here, we study lifestyles in the context of this whole. We first use machine learning to reconstruct the expression changes underlying life cycle progression in the bacterium Bacillus subtilis, based on hundreds of previously acquired expression profiles. This yields a timeli
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- van Gestel, Jordi
- Ackermann, Martin
- Wagner, Andreas
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Citations
van Gestel, J., Ackermann, M., & Wagner, A. (2019). Microbial life cycles link global modularity in regulation to mosaic evolution. Nature Ecology and Evolution, 3(8), 1184–1196. https://doi.org/10.1038/s41559-019-0939-6
