Publication: Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters
Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters
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Anwer, M. S., & Stieger, B. (2014). Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters. Pflügers Archiv : European Journal of Physiology, 466(1), 77–89. https://doi.org/10.1007/s00424-013-1367-0
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The SLC10A transporter gene family consists of seven members and substrates transported by three members (SLC10A1, SLC10A2 and SLC10A6) are Na(+)-dependent. SLC10A1 (sodium taurocholate cotransporting polypeptide [NTCP]) and SLC10A2 (apical sodium-dependent bile salt transporter [ASBT]) transport bile salts and play an important role in maintaining enterohepatic circulation of bile salts. Solutes other than bile salts are also transported by NTCP. However, ASBT has not been shown to be a transporter for non-bile salt substrates. While
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Anwer, M. S., & Stieger, B. (2014). Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters. Pflügers Archiv : European Journal of Physiology, 466(1), 77–89. https://doi.org/10.1007/s00424-013-1367-0