Publication: A xenograft model of high risk leukemia reveals an oligoclonal composition of leukemia initiating cells
A xenograft model of high risk leukemia reveals an oligoclonal composition of leukemia initiating cells
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Schmitz, M. (2011). A xenograft model of high risk leukemia reveals an oligoclonal composition of leukemia initiating cells. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-59685
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Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood and occurs in the bone marrow and blood. Patients can be effectively cured with combinatorial chemotherapy in 80% of cases, but the high toxicity of the treatment and the frequency of relapses still are major obstacles and lead to high mortality. Based on current treatment protocols of one of the biggest study groups on childhood ALL, the BFM study group (named after Berlin-Frankfurt-Münster, to credit the founding members), a group of patients can be identified
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Schmitz, M. (2011). A xenograft model of high risk leukemia reveals an oligoclonal composition of leukemia initiating cells. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-59685
