Publication: To B-(RAF) or not to be
To B-(RAF) or not to be
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Date
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Dummer, R., Goldinger, S. M., Widmer, D., Dreier, J., & Levesque, M. P. (2014). To B-(RAF) or not to be. Journal of Investigative Dermatology, 134(5), 1200–1201. https://doi.org/10.1038/jid.2014.62
Abstract
Abstract
Abstract
The identification of targetable mutations has revolutionized the therapy of metastatic melanoma. In particular, BRAF and MEK inhibitors have a well-documented impact on overall survival in metastatic disease. However, therapeutic success is highly dependent on the correct identification of these mutations. We discuss the impact of molecular heterogeneity in this context.
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Creators (Authors)
- Dummer, Reinhard
- Goldinger, Simone M
- Widmer, Daniel
- Dreier, Jil
- Levesque, Mitchell P
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Citations
Dummer, R., Goldinger, S. M., Widmer, D., Dreier, J., & Levesque, M. P. (2014). To B-(RAF) or not to be. Journal of Investigative Dermatology, 134(5), 1200–1201. https://doi.org/10.1038/jid.2014.62