Publication: Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy
Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy
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Volk, C., Jaramillo, V., Merki, R., O’Gorman Tuura, R., & Huber, R. (2018). Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy. Human Brain Mapping, 39, 3984–3992. https://doi.org/10.1002/hbm.24225
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Abstract
The glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor is involved in synaptic plasticity processes, and animal studies have demonstrated altered expression across the sleep wake cycle. Accordingly, glutamate levels are reduced during non-rapid eye movement (NREM) sleep and the rate of this decrease is positively correlated with sleep EEG slow wave activity (SWA). Here, we combined proton magnetic resonance spectroscopy ( H-MRS) and high-density sleep EEG to assess if H-MRS is sensitive to diurnal chan
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- Volk, Carina
- Jaramillo, Valeria
- Merki, Renato
- O'Gorman Tuura, Ruth
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Volk, C., Jaramillo, V., Merki, R., O’Gorman Tuura, R., & Huber, R. (2018). Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy. Human Brain Mapping, 39, 3984–3992. https://doi.org/10.1002/hbm.24225
