The prognostic value of Indoleamine-2,3-Dioxygenase Gene Expression in Urine of Prostate cancer Patients Undergoing Radical Prostatectomy as First Treatment of Choice

Abstract

Prostate cancer (PCa) is a slow-growing tumor representing one of the major causes of all new cancer cases and cancer mortality in men worldwide. Although screening methods for PCa have substantially improved, the outcome for patients with advanced PCa remains poor. The elucidation of the molecular mechanism that drives the progression from a slow-growing, organ-confined tumor to a highly invasive and castration-resistant PCa (CRPC) is therefore important. We have already proved the diagnostic potential of indoleamine-2,3-dioxygenase Show more