Publication: The Circular RNA Predicts Survival in Critically Ill Patients With Acute Kidney Injury
The Circular RNA Predicts Survival in Critically Ill Patients With Acute Kidney Injury
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Kölling, M., Seeger, H., Haddad, G., Kistler, A., Nowak, A., Faulhaber-Walter, R., Kielstein, J., Haller, H., Fliser, D., Mueller, T., Wüthrich, R. P., & Lorenzen, J. M. (2018). The Circular RNA Predicts Survival in Critically Ill Patients With Acute Kidney Injury. Kidney International Reports, 3(5), 1144–1152. https://doi.org/10.1016/j.ekir.2018.05.012
Abstract
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Abstract
Introduction Circular RNAs (circRNAs) have recently been described as novel noncoding regulators of gene expression. They might have an impact on microRNA expression by their sponging activity. The detectability in blood of these RNA transcripts has been demonstrated in patients with cancer and cardiovascular disease. We tested the hypothesis that circulating circRNAs in blood of critically ill patients with acute kidney injury (AKI) at inception of renal replacement therapy may also be dysregulated and associated with patient surviv
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- Kölling, Malte
- Seeger, Harald
- Haddad, George
- Kistler, Andreas
- Nowak, Albina
- Faulhaber-Walter, Robert
- Kielstein, Jan
- Haller, Hermann
- Fliser, Danilo
- Mueller, Thomas
- Wüthrich, Rudolf P
- Lorenzen, Johan M
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Kölling, M., Seeger, H., Haddad, G., Kistler, A., Nowak, A., Faulhaber-Walter, R., Kielstein, J., Haller, H., Fliser, D., Mueller, T., Wüthrich, R. P., & Lorenzen, J. M. (2018). The Circular RNA Predicts Survival in Critically Ill Patients With Acute Kidney Injury. Kidney International Reports, 3(5), 1144–1152. https://doi.org/10.1016/j.ekir.2018.05.012
