Publication: Autophagy Proteins in the Restriction of Kaposi Sarcoma-Associated Herpesvirus Entry
Autophagy Proteins in the Restriction of Kaposi Sarcoma-Associated Herpesvirus Entry
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Schmidt, K. W. (2024). Autophagy Proteins in the Restriction of Kaposi Sarcoma-Associated Herpesvirus Entry. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-259626
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When microorganisms invade host cells and access the cytoplasm, host defense mechanisms are deployed to direct pathogens to degradation by selective autophagy. Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic ɣ-herpesvirus associated with several opportunistic malignancies, including the fourth most common cancer in sub-Saharan Africa, Kaposi sarcoma. Numerous studies have investigated autophagy upon lytic reactivation of KSHV, however autophagy involvement in KSHV entry has remained unexplored. Using in vitro infection of
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Schmidt, K. W. (2024). Autophagy Proteins in the Restriction of Kaposi Sarcoma-Associated Herpesvirus Entry. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-259626