Publication: Increased number of islet-associated macrophages in type 2 diabetes
Increased number of islet-associated macrophages in type 2 diabetes
Date
Date
Date
Citations
Ehses, J. A., Perren, A., Eppler, E., Ribaux, P., Pospisilik, J. A., Maor-Cahn, R., Gueripel, X., Ellingsgaard, H., Schneider, M. K. J., Biollaz, G., Fontana, A., Reinecke, M., Homo-Delarche, F., & Donath, M. Y. (2007). Increased number of islet-associated macrophages in type 2 diabetes. Diabetes, 56(9), 2356–2370. https://doi.org/10.2337/db06-1650
Abstract
Abstract
Abstract
Activation of the innate immune system in obesity is a risk factor for the development of type 2 diabetes. The aim of the current study was to investigate the notion that increased numbers of macrophages exist in the islets of type 2 diabetes patients and that this may be explained by a dysregulation of islet-derived inflammatory factors. Increased islet-associated immune cells were observed in human type 2 diabetic patients, high-fat-fed C57BL/6J mice, the GK rat, and the db/db mouse. When cultured islets were exposed to a type 2 dia
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Ehses, J A
- Perren, A
- Eppler, E
- Ribaux, P
- Pospisilik, J A
- Maor-Cahn, R
- Gueripel, X
- Ellingsgaard, H
- Schneider, M K J
- Biollaz, G
- Fontana, A
- Reinecke, M
- Homo-Delarche, F
- Donath, M Y
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
Additional Information
Additional Information
Additional Information
OA Status
OA Status
OA Status
Publisher DOI
Metrics
Downloads
Views
Citations
Ehses, J. A., Perren, A., Eppler, E., Ribaux, P., Pospisilik, J. A., Maor-Cahn, R., Gueripel, X., Ellingsgaard, H., Schneider, M. K. J., Biollaz, G., Fontana, A., Reinecke, M., Homo-Delarche, F., & Donath, M. Y. (2007). Increased number of islet-associated macrophages in type 2 diabetes. Diabetes, 56(9), 2356–2370. https://doi.org/10.2337/db06-1650
