Publication:

Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens

Date

Date

Date
2009
Journal Article
Published version

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Citation copied

Dip, R., Lenz, S., Gmuender, H., & Naegeli, H. (2009). Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens. Food and Chemical Toxicology, 47, 787–795. https://doi.org/10.1016/j.fct.2009.01.008

Abstract

Abstract

Abstract

Combinations of estrogen receptor agonists have been shown to exert more potent effects than single compounds in many single-endpoint bioassays. However, to our knowledge, it has never been tested how genome-wide expression programs are shaped by the interplay of multiple estrogenic stimuli. In view of the abundance of dietary phytoestrogens, we selected binary mixtures of these phytochemicals to determine their global impact using high-density DNA microarrays. MCF7 cells, a frequent in vitro model for molecular processes associated w

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2 since deposited on 2009-03-31
Acq. date: 2025-11-12

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132 since deposited on 2009-03-31
Acq. date: 2025-11-12

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Creators (Authors)

  • Dip, R
    affiliation.icon.alt
  • Lenz, S
    affiliation.icon.alt
  • Gmuender, H
    affiliation.icon.alt
  • Naegeli, H
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
47

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
787

Page end

Page end

Page end
795

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2009

Date available

Date available

Date available
2009-03-31

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0278-6915

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

2 since deposited on 2009-03-31
Acq. date: 2025-11-12

Views

132 since deposited on 2009-03-31
Acq. date: 2025-11-12

Citations

Citation copied

Dip, R., Lenz, S., Gmuender, H., & Naegeli, H. (2009). Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens. Food and Chemical Toxicology, 47, 787–795. https://doi.org/10.1016/j.fct.2009.01.008

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