Cognitive and emotional impairments in adults with attention-deficit/hyperactivity disorder and cocaine use

Wunderli, Michael D; Vonmoos, Matthias; Niedecker, Stefania M; Hulka, Lea M; Preller, Katrin H; Baumgartner, Markus R; Kraemer, Thomas; Seifritz, Erich; Schaub, Michael P; Eich-Höchli, Dominique; Quednow, Boris B

doi:10.1016/j.drugalcdep.2016.03.026

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Wunderli, M. D., Vonmoos, M., Niedecker, S. M., Hulka, L. M., Preller, K. H., Baumgartner, M. R., Kraemer, T., Seifritz, E., Schaub, M. P., Eich-Höchli, D., & Quednow, B. B. (2016). Cognitive and emotional impairments in adults with attention-deficit/hyperactivity disorder and cocaine use. Drug and Alcohol Dependence, 163, 92–99. https://doi.org/10.1016/j.drugalcdep.2016.03.026

Abstract

BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is an important modulator of cognitive and social functioning in cocaine addiction but it is unclear whether ADHD symptoms and cocaine use display mutually aggravating interaction effects on cognition, social functioning, and depressive symptoms. Therefore, we investigated the interaction of cocaine use and adult ADHD on social and non-social cognition and depressive symptoms. METHODS: Twenty-four cocaine users with (CU+ADHD) and 30 without ADHD (CU-ADHD), 29 cocaine-naïve AD