Publication: Assessment of brain responses to innocuous and noxious electrical forepaw stimulation in mice using BOLD fMRI
Assessment of brain responses to innocuous and noxious electrical forepaw stimulation in mice using BOLD fMRI
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Bosshard, S. C., Baltes, C., Wyss, M. T., Mueggler, T., Weber, B., & Rudin, M. (2010). Assessment of brain responses to innocuous and noxious electrical forepaw stimulation in mice using BOLD fMRI. Pain, 151(3), 655–663. https://doi.org/10.1016/j.pain.2010.08.025
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Functional magnetic resonance imaging (fMRI) using the blood oxygen level-dependent (BOLD) contrast was used to study sensory processing in the brain of isoflurane-anesthetized mice. The use of a cryogenic surface coil in a small animal 9.4T system provided the sensitivity required for detection and quantitative analysis of hemodynamic changes caused by neural activity in the mouse brain in response to electrical forepaw stimulation at different amplitudes. A gradient echo-echo planar imaging (GE-EPI) sequence was used to acquire five
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- Bosshard, S C
- Baltes, C
- Wyss, M T
- Mueggler, T
- Weber, B
- Rudin, M
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Bosshard, S. C., Baltes, C., Wyss, M. T., Mueggler, T., Weber, B., & Rudin, M. (2010). Assessment of brain responses to innocuous and noxious electrical forepaw stimulation in mice using BOLD fMRI. Pain, 151(3), 655–663. https://doi.org/10.1016/j.pain.2010.08.025