Publication: PET/CT radiomics for prediction of hyperprogression in metastatic melanoma patients treated with immune checkpoint inhibitors
PET/CT radiomics for prediction of hyperprogression in metastatic melanoma patients treated with immune checkpoint inhibitors
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Gabryś, H. S., Basler, L., Burgermeister, S., Hogan, S., Ahmadsei, M., Pavic, M., Bogowicz, M., Vuong, D., Tanadini-Lang, S., Förster, R., Kudura, K., Huellner, M., Dummer, R., Levesque, M. P., & Guckenberger, M. (2022). PET/CT radiomics for prediction of hyperprogression in metastatic melanoma patients treated with immune checkpoint inhibitors. Frontiers in Oncology, 12, 977822. https://doi.org/10.3389/fonc.2022.977822
Abstract
Abstract
Abstract
PurposeThis study evaluated pretreatment 2[18F]fluoro-2-deoxy-D-glucose (FDG)-PET/CT-based radiomic signatures for prediction of hyperprogression in metastatic melanoma patients treated with immune checkpoint inhibition (ICI).Material and methodFifty-six consecutive metastatic melanoma patients treated with ICI and available imaging were included in the study and 330 metastatic lesions were individually, fully segmented on pre-treatment CT and FDG-PET imaging. Lesion hyperprogression (HPL) was defined as lesion progression according t
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Creators (Authors)
- Gabryś, H S
- Basler, Lucas
- Burgermeister, Simon
- Hogan, Sabrina
- Ahmadsei, Maiwand
- Pavic, Matea
- Bogowicz, Marta
- Vuong, Diem
- Tanadini-Lang, Stephanie
- Kudura, Ken
- Huellner, Martin
- Dummer, Reinhard
- Levesque, M P
- Guckenberger, Matthias
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Gabryś, H. S., Basler, L., Burgermeister, S., Hogan, S., Ahmadsei, M., Pavic, M., Bogowicz, M., Vuong, D., Tanadini-Lang, S., Förster, R., Kudura, K., Huellner, M., Dummer, R., Levesque, M. P., & Guckenberger, M. (2022). PET/CT radiomics for prediction of hyperprogression in metastatic melanoma patients treated with immune checkpoint inhibitors. Frontiers in Oncology, 12, 977822. https://doi.org/10.3389/fonc.2022.977822
