Publication: Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators
Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators
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Musso, G., Mosimann, C., Panáková, D., Burger, A., Zhou, Y., Zon, L. I., & MacRae, C. A. (2015). Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators. Genomics Data, 6, 199–201. https://doi.org/10.1016/j.gdata.2015.09.015
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The vertebrate heart develops from two distinct lineages of cardiomyocytes that arise from the first and second heart fields (FHF and SHF, respectively). The FHF forms the primitive heart tube, while adding cells from the SHF allows elongation at both poles of the tube. Initially seen as an exclusive characteristic of higher vertebrates, recent work has demonstrated the presence of a distinct FHF and SHF in lower vertebrates, including zebrafish. We found that key transcription factors that regulate septation and chamber formation in
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Musso, G., Mosimann, C., Panáková, D., Burger, A., Zhou, Y., Zon, L. I., & MacRae, C. A. (2015). Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators. Genomics Data, 6, 199–201. https://doi.org/10.1016/j.gdata.2015.09.015