Publication: Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response
Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response
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Picart-Picolo, A., Grob, S., Picault, N., Franek, M., Llauro, C., Halter, T., Maier, T. R., Jobet, E., Descombin, J., Zhang, P., Paramasivan, V., Baum, T. J., Navarro, L., Dvořáčková, M., Mirouze, M., & Pontvianne, F. (2020). Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response. Genome Research, 30(11), 1583–1592. https://doi.org/10.1101/gr.261586.120
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Rapid plant genome evolution is crucial to adapt to environmental changes. Chromosomal rearrangements and gene copy number variation (CNV) are two important tools for genome evolution and sources for the creation of new genes. However, their emergence takes many generations. In this study, we show that in Arabidopsis thaliana, a significant loss of ribosomal RNA (rRNA) genes with a past history of a mutation for the chromatin assembly factor 1 (CAF1) complex causes rapid changes in the genome structure. Using long-read sequencing and
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Picart-Picolo, A., Grob, S., Picault, N., Franek, M., Llauro, C., Halter, T., Maier, T. R., Jobet, E., Descombin, J., Zhang, P., Paramasivan, V., Baum, T. J., Navarro, L., Dvořáčková, M., Mirouze, M., & Pontvianne, F. (2020). Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response. Genome Research, 30(11), 1583–1592. https://doi.org/10.1101/gr.261586.120