Publication:

Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies

Date

Date

Date
2012
Journal Article
Published version

Citations

Citation copied

Abela, I. A., Berlinger, L., Schanz, M., Reynell, L., Günthard, H. F., Rusert, P., & Trkola, A. (2012). Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies. PLoS Pathogens, 8(4), e1002634. https://doi.org/10.1371/journal.ppat.1002634

Abstract

Abstract

Abstract

HIV is known to spread efficiently both in a cell-free state and from cell to cell, however the relative importance of the cell-cell transmission mode in natural infection has not yet been resolved. Likewise to what extent cell-cell transmission is vulnerable to inhibition by neutralizing antibodies and entry inhibitors remains to be determined. Here we report on neutralizing antibody activity during cell-cell transmission using specifically tailored experimental strategies which enable unambiguous discrimination between the two trans

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101 since deposited on 2012-12-13
Acq. date: 2025-11-12

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158 since deposited on 2012-12-13
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

  • Abela, Irene A
    affiliation.icon.alt
  • Berlinger, Livia
    affiliation.icon.alt
  • Schanz, Merle
    affiliation.icon.alt
  • Reynell, Lucy
    affiliation.icon.alt
  • Günthard, Huldrych F
    affiliation.icon.alt
  • Rusert, Peter
    affiliation.icon.alt
  • Trkola, Alexandra
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
8

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
e1002634

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2012

Date available

Date available

Date available
2012-12-13

Publisher

Publisher

Publisher

Series Name

Series Name

Series Name
PLoS Pathogens

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1553-7366

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

101 since deposited on 2012-12-13
Acq. date: 2025-11-12

Views

158 since deposited on 2012-12-13
Acq. date: 2025-11-12

Citations

Citation copied

Abela, I. A., Berlinger, L., Schanz, M., Reynell, L., Günthard, H. F., Rusert, P., & Trkola, A. (2012). Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies. PLoS Pathogens, 8(4), e1002634. https://doi.org/10.1371/journal.ppat.1002634

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