Publication: Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention
Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention
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Grunig, G., Eichstaedt, C. A., Verweyen, J., Durmus, N., Saxer, S., Krafsur, G., Stenmark, K., Ulrich, S., Grünig, E., & Pylawka, S. (2018). Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. Frontiers in Physiology, 9, 955. https://doi.org/10.3389/fphys.2018.00955
Abstract
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Abstract
Rationale: Therapeutic exercise training has been shown to significantly improve pulmonary hypertension (PH), including 6-min walking distance and right heart function. Supplemental nightly oxygen also has therapeutic effects. A biomarker tool that could query critical gene networks would aid in understanding the molecular effects of the interventions. Methods: Paired bio-banked serum (n = 31) or plasma (n = 21) samples from the exercise or oxygen intervention studies, respectively, and bio-banked plasma samples (n = 20) from high alt
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- Grunig, Gabriele
- Eichstaedt, Christina A
- Verweyen, Jeremias
- Durmus, Nedim
- Saxer, Stephanie
- Krafsur, Greta
- Stenmark, Kurt
- Ulrich, Silvia
- Grünig, Ekkehard
- Pylawka, Serhiy
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Grunig, G., Eichstaedt, C. A., Verweyen, J., Durmus, N., Saxer, S., Krafsur, G., Stenmark, K., Ulrich, S., Grünig, E., & Pylawka, S. (2018). Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. Frontiers in Physiology, 9, 955. https://doi.org/10.3389/fphys.2018.00955
