Publication: Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction
Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction
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Araya, S., Kuster, E., Gluch, D., Mariotta, L., Lutz, C., Reding, T. V., Graf, R., Verrey, F., & Camargo, S. M. R. (2018). Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 314(4), G517–G536. https://doi.org/10.1152/ajpgi.00135.2017
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Glutamine (Gln) is the most concentrated amino acid in blood and considered conditionally essential. Its requirement is increased during physiological stress, such as malnutrition or illness, despite its production by muscle and other organs. In the malnourished state Gln has been suggested to have a trophic effect on the exocrine pancreas and small intestine. However, the Gln transport capacity, the functional relationship of these two organs and the potential role of the Gln-glutamate (Glu) cycle are unknown. We observed that pancre
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- Araya, Selene
- Kuster, Evelyne
- Gluch, Dino
- Mariotta, Luca
- Lutz, Christian
- Reding, Theresia V
- Graf, Rolf
- Verrey, François
- Camargo, Simone M.R
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Araya, S., Kuster, E., Gluch, D., Mariotta, L., Lutz, C., Reding, T. V., Graf, R., Verrey, F., & Camargo, S. M. R. (2018). Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 314(4), G517–G536. https://doi.org/10.1152/ajpgi.00135.2017