Publication: Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis
Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis
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Schlossberger, V., Worni, M., Kihm, C., Montani, M., Datz, C., Hampe, J., & Stickel, F. (2019). Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis. Gut and Liver, 13(1), 77–82. https://doi.org/10.5009/gnl18037
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Background/Aims Noninvasive markers of liver fibrosis in alcoholic liver disease (ALD) are crucial to establish early intervention. Previous studies have suggested that plasma levels of cleaved keratin-18 (K18; M30) fragments can predict the severity of liver disease. The aim of this study was to correlate plasma M30 levels with stages of liver fibrosis in ALD. Methods Patients with ALD (n=139, 79.1% males) and liver histology were included, and plasma samples were collected to quantify plasma M30 levels. Patients were stratified i
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- Schlossberger, Viola
- Worni, Mathias
- Montani, Matteo
- Datz, Christian
- Hampe, Jochen
- Stickel, Felix
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Schlossberger, V., Worni, M., Kihm, C., Montani, M., Datz, C., Hampe, J., & Stickel, F. (2019). Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis. Gut and Liver, 13(1), 77–82. https://doi.org/10.5009/gnl18037
