Publication: Hemostatic properties and the role of cell receptor recognition in human hair keratin protein hydrogels
Hemostatic properties and the role of cell receptor recognition in human hair keratin protein hydrogels
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Burnett, L. R., Rahmany, M. B., Richter, J. R., Aboushwareb, T. A., Eberli, D., Ward, C. L., Orlando, G., Hantgan, R. R., & Van Dyke, M. E. (2013). Hemostatic properties and the role of cell receptor recognition in human hair keratin protein hydrogels. Biomaterials, 34, 2632–2640. https://doi.org/10.1016/j.biomaterials.2012.12.022
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Driven by new discoveries in stem-cell biology and regenerative medicine, there is broad interest in biomaterials that go beyond basic interactions with cells and tissues to actively direct and sustain cellular behavior. Keratin biomaterials have the potential to achieve these goals but have been inadequately described in terms of composition, structure, and cell-instructive characteristics. In this manuscript we describe and characterize a keratin-based biomaterial, demonstrate self-assembly of cross-linked hydrogels, investigate a c
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Burnett, L. R., Rahmany, M. B., Richter, J. R., Aboushwareb, T. A., Eberli, D., Ward, C. L., Orlando, G., Hantgan, R. R., & Van Dyke, M. E. (2013). Hemostatic properties and the role of cell receptor recognition in human hair keratin protein hydrogels. Biomaterials, 34, 2632–2640. https://doi.org/10.1016/j.biomaterials.2012.12.022