Publication:

Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries

Date

Date

Date
2025
Journal Article
Published version

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Schweizer, T. A., Würmli, J. S., Prinz, J., Wölfle, M., Marti, R., Koliwer-Brandl, H., Rooney, A. M., Benvenga, V., Egli, A., Imhof, L., Bosshard, P. P., & Achermann, Y. (2025). Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries. Microorganisms, 13(1), 204. https://doi.org/10.3390/microorganisms13010204

Abstract

Abstract

Abstract

Classical preoperative skin antisepsis is insufficient in completely eliminating bacterial skin colonization for arthroplasty. In contrast, photodynamic therapy (PDT) with red light and methyl-aminolevulinate (MAL), combined with skin antisepsis, led to the absence of bacterial growth in healthy participants, though with local skin erythema, posing an obstacle for orthopedic surgery. Therefore, we explored whether artificial daylight PDT (PDT-DL) was superior to red light. Twenty healthy participants were allocated to either 5-aminole

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11 since deposited on 2025-01-27
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Acq. date: 2025-11-12

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34 since deposited on 2025-01-27
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Acq. date: 2025-11-12

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Creators (Authors)

  • Schweizer, Tiziano A
  • Würmli, Julia S
  • Prinz, Julia
  • Wölfle, Maximilian
  • Marti, Roger
  • Koliwer-Brandl, Hendrik
  • Rooney, Ashley M
  • Benvenga, Vanni
  • Egli, Adrian
  • Imhof, Laurence
  • Bosshard, Philipp P

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
13

Number

Number

Number
1

Page range/Item number

Page range/Item number

Page range/Item number
204

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2025-01-18

Date available

Date available

Date available
2025-01-27

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2076-2607

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

11 since deposited on 2025-01-27
8last week
Acq. date: 2025-11-12

Views

34 since deposited on 2025-01-27
31last week
Acq. date: 2025-11-12

Citations

Citations

Citation copied

Schweizer, T. A., Würmli, J. S., Prinz, J., Wölfle, M., Marti, R., Koliwer-Brandl, H., Rooney, A. M., Benvenga, V., Egli, A., Imhof, L., Bosshard, P. P., & Achermann, Y. (2025). Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries. Microorganisms, 13(1), 204. https://doi.org/10.3390/microorganisms13010204

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