Publication: Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals
Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals
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Barreira da Silva, R., & Münz, C. (2011). Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals. Cellular and Molecular Life Sciences, 68(21), 3505–3518. https://doi.org/10.1007/s00018-011-0801-8
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Natural killer (NK) cells have originally been identified by their spontaneous cytolytic potential against tumor cells, which, however, might result from pre-activation due to prior pathogen exposure. Resting NK cells, on the contrary, require activation by bystander antigen-presenting cells to reach their full functional competence. In this review, we will summarize studies on how dendritic cells (DCs), the most potent type of antigen-presenting cell, communicate with human NK cells to activate them in secondary lymphoid organs and t
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- Barreira da Silva, R
- Münz, C
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Barreira da Silva, R., & Münz, C. (2011). Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals. Cellular and Molecular Life Sciences, 68(21), 3505–3518. https://doi.org/10.1007/s00018-011-0801-8
