Publication: 7Hsp70 serum levels in pet dogs - a potential diagnostic biomarker for spontaneous round cell tumors
7Hsp70 serum levels in pet dogs - a potential diagnostic biomarker for spontaneous round cell tumors
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Salvermoser, L., Dressel, S., Schleißheimer, S., Stangl, S., Diederichs, C., Wergin, M., Rohrer Bley, C., Haller, B., & Multhoff, G. (2019). 7Hsp70 serum levels in pet dogs - a potential diagnostic biomarker for spontaneous round cell tumors. Cell Stress & Chaperones, 24, 969–978. https://doi.org/10.1007/s12192-019-01024-9
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The concentration of circulating heat shock protein 70 (Hsp70) was measured in liquid biopsies of canine tumor patients as a potential biomarker. Compared with rodent tumor models, spontaneously occurring tumors in pet dogs reflect the clinical situation of human patients better, as dogs cohabitate with their owners in the same environment, reach a much older age than rodents, can provide blood samples much more frequently, and receive up-to-date medical care and, similar to humans, their tumors show a high genetic heterogeneity. Due
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Salvermoser, L., Dressel, S., Schleißheimer, S., Stangl, S., Diederichs, C., Wergin, M., Rohrer Bley, C., Haller, B., & Multhoff, G. (2019). 7Hsp70 serum levels in pet dogs - a potential diagnostic biomarker for spontaneous round cell tumors. Cell Stress & Chaperones, 24, 969–978. https://doi.org/10.1007/s12192-019-01024-9