Publication:

From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis

Date

Date

Date
2023
Journal Article
Published version

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Grünblatt, E., Homolak, J., Babic Perhoc, A., Davor, V., Knezovic, A., Osmanovic Barilar, J., Riederer, P., Walitza, S., Tackenberg, C., & Salkovic-Petrisic, M. (2023). From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis. Frontiers in Neuroscience, 17, 1104985. https://doi.org/10.3389/fnins.2023.1104985

Abstract

Abstract

Abstract

Alzheimer’s disease (AD) is the most common neurodegenerative disorder with the majority of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved. Though sAD is argued to be a polygenic disorder, apolipoprotein E (APOE) ε4, was found three decades ago to pose the strongest genetic risk for sAD. Currently, the only clinically approved disease-modifying drugs for AD are aducanumab (Aduhelm) and lecanemab (Leqembi). All other AD treatment options are purely symptomatic with modest benefits. Similarly, att

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78 since deposited on 2023-02-20
Acq. date: 2025-11-13

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129 since deposited on 2023-02-20
Acq. date: 2025-11-13

Additional indexing

Creators (Authors)

  • Grünblatt, Edna
  • Homolak, Jan
  • Babic Perhoc, Ana
  • Davor, Virag
  • Knezovic, Ana
  • Osmanovic Barilar, Jelena
  • Riederer, Peter
  • Walitza, Susanne
  • Tackenberg, Christian
  • Salkovic-Petrisic, Melita

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
17

Page range/Item number

Page range/Item number

Page range/Item number
1104985

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

General Neuroscience

Language

Language

Language
English

Publication date

Publication date

Publication date
2023-02-16

Date available

Date available

Date available
2023-02-20

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1662-453X

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

78 since deposited on 2023-02-20
Acq. date: 2025-11-13

Views

129 since deposited on 2023-02-20
Acq. date: 2025-11-13

Citations

Citation copied

Grünblatt, E., Homolak, J., Babic Perhoc, A., Davor, V., Knezovic, A., Osmanovic Barilar, J., Riederer, P., Walitza, S., Tackenberg, C., & Salkovic-Petrisic, M. (2023). From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis. Frontiers in Neuroscience, 17, 1104985. https://doi.org/10.3389/fnins.2023.1104985

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