Publication: HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
Date
Date
Date
Citations
Marcu, A., Bichmann, L., Kuchenbecker, L., Kowalewski, D. J., Freudenmann, L. K., Backert, L., Mühlenbruch, L., Szolek, A., Lübke, M., Wagner, P., Engler, T., Matovina, S., Wang, J., Hauri-Hohl, M., Martin, R., Kapolou, K., Walz, J. S., Velz, J., Moch, H., … Neidert, M. C. (2021). HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy. Journal for ImmunoTherapy of Cancer, 9(4), 18. https://doi.org/10.1136/jitc-2020-002071
Abstract
Abstract
Abstract
BACKGROUND
The human leucocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Understanding the benign HLA ligand repertoire is a prerequisite to define safe T-cell-based immunotherapies against cancer. Due to the poor availability of benign tissues, if available, normal tissue adjacent to the tumor has been used as a benign surrogate when defining tumor-associated antigens. However, this comparison has proven to be insufficient
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Marcu, Ana
- Bichmann, Leon
- Kuchenbecker, Leon
- Kowalewski, Daniel Johannes
- Freudenmann, Lena Katharina
- Backert, Linus
- Mühlenbruch, Lena
- Szolek, András
- Lübke, Maren
- Wagner, Philipp
- Engler, Tobias
- Matovina, Sabine
- Wang, Jian
- Hauri-Hohl, Mathias
- Martin, Roland
- Kapolou, Konstantina
- Walz, Juliane Sarah
- Velz, Julia
- Moch, Holger
- Regli, Luca
- Silginer, Manuela
- Weller, Michael
- Löffler, Markus W
- Erhard, Florian
- Schlosser, Andreas
- Kohlbacher, Oliver
- Stevanović, Stefan
- Rammensee, Hans-Georg
- Neidert, Marian Christoph
Volume
Volume
Volume
Number
Number
Number
Page Range
Page Range
Page Range
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Marcu, A., Bichmann, L., Kuchenbecker, L., Kowalewski, D. J., Freudenmann, L. K., Backert, L., Mühlenbruch, L., Szolek, A., Lübke, M., Wagner, P., Engler, T., Matovina, S., Wang, J., Hauri-Hohl, M., Martin, R., Kapolou, K., Walz, J. S., Velz, J., Moch, H., … Neidert, M. C. (2021). HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy. Journal for ImmunoTherapy of Cancer, 9(4), 18. https://doi.org/10.1136/jitc-2020-002071
