Menopause is associated with decreased postprandial ghrelin, while a history of anorexia nervosa is associated with increased total ghrelin

Stojiljkovic-Drobnjak, Suzana; Fischer, Susanne; Arnold, Myrtha; Langhans, Wolfgang; Ehlert, Ulrike

doi:10.5167/uzh-158264

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Stojiljkovic-Drobnjak, S., Fischer, S., Arnold, M., Langhans, W., & Ehlert, U. (2019). Menopause is associated with decreased postprandial ghrelin, while a history of anorexia nervosa is associated with increased total ghrelin. Journal of Neuroendocrinology, 31, e12661. https://doi.org/10.1111/jne.12661

Abstract

INTRODUCTION: Middle age has been linked with various dysfunctional eating patterns in women. The hormone ghrelin is related to food intake, with plasma levels rising before eating and decreasing immediately afterwards. Animal research has shown that estradiol is an antagonist of ghrelin. Given that both menopause and anorexia nervosa (AN) are states characterised by reduced estradiol, the goal of the present study was to investigate for the first time whether menopausal status and a history of AN are linked with altered ghrelin level