Publication: Anesthetic-induced improvement of the inflammatory response to one-lung ventilation
Anesthetic-induced improvement of the inflammatory response to one-lung ventilation
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De Conno, E., Steurer, M. P., Wittlinger, M., Zalunardo, M. P., Weder, W., Schneiter, D., Schimmer, R. C., Klaghofer, R., Neff, T. A., Schmid, E. R., Spahn, D. R., Roth Z’graggen, B., Urner, M., & Beck-Schimmer, B. (2009). Anesthetic-induced improvement of the inflammatory response to one-lung ventilation. Anesthesiology, 110(6), 1316–1326. https://doi.org/10.1097/ALN.0b013e3181a10731
Abstract
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BACKGROUND: Although one-lung ventilation (OLV) has become an established procedure during thoracic surgery, sparse data exist about inflammatory alterations in the deflated, reventilated lung. The aim of this study was to prospectively investigate the effect of OLV on the pulmonary inflammatory response and to assess possible immunomodulatory effects of the anesthetics propofol and sevoflurane. METHODS: Fifty-four adults undergoing thoracic surgery with OLV were randomly assigned to receive either anesthesia with intravenously applie
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- De Conno, E
- Steurer, M P
- Wittlinger, M
- Zalunardo, M P
- Weder, W
- Schneiter, D
- Schimmer, R C
- Klaghofer, R
- Neff, T A
- Schmid, E R
- Spahn, D R
- Roth Z'graggen, B
- Urner, M
- Beck-Schimmer, B
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De Conno, E., Steurer, M. P., Wittlinger, M., Zalunardo, M. P., Weder, W., Schneiter, D., Schimmer, R. C., Klaghofer, R., Neff, T. A., Schmid, E. R., Spahn, D. R., Roth Z’graggen, B., Urner, M., & Beck-Schimmer, B. (2009). Anesthetic-induced improvement of the inflammatory response to one-lung ventilation. Anesthesiology, 110(6), 1316–1326. https://doi.org/10.1097/ALN.0b013e3181a10731
